Content area

|
|

Hjernens biologiske ur

Forfatter(e)
Jan Fahrenkrug Klinisk Biokemisk Afdeling, Bispebjerg og Frederiksberg Hospital

Ugeskr Læger 2018;180:V03180212
Reference: 
Ugeskr Læger 2018;180:V03180212
Blad nummer: 

Summary

Jan Fahrenkrug:

The brain’s biological clock

Ugeskr Læger 2018;180:V03180212

Daily biological rhythms are controlled by a clock system, composed of a hierarchical multi-oscillator structure. Each cell in this system harbours a self-sustained autonomous molecular oscillator. Light adjusts the phase of the brain oscillator to the environmental light/dark cycle by intrinsically photosensitive retinal ganglion cells through their own photoreceptor, melanopsin, and by using the neuropeptide called pituitary adenylate cyclase-activating polypeptide as well as glutamate as neurotransmitters. The circadian synchronisation system is critical to health, and breakdown of the 24-hours temporal order could lead to pathological conditions.

Du skal være logget ind for at læse denne artikel
Log ind

Right side

af Tom Buur | 20/07
3 kommentarer
af Niels Albert Graudal | 16/07
4 kommentarer
af Christian F. Asmussen | 15/07
1 Kommentar
af Christian F. Asmussen | 15/07
1 Kommentar
af Jørgen Alving | 12/07
2 kommentarer
af Mogens Holbech Dahl | 10/07
3 kommentarer
af Elisabeth Sirkka Augustina Bright | 06/07
2 kommentarer
af Lars Høj | 06/07
1 Kommentar
af Christian E. H. R. Freitag | 04/07
8 kommentarer