Content area

|
|

Hjernens biologiske ur

Forfatter(e)
Jan Fahrenkrug Klinisk Biokemisk Afdeling, Bispebjerg og Frederiksberg Hospital

Ugeskr Læger 2018;180:V03180212
Reference: 
Ugeskr Læger 2018;180:V03180212
Blad nummer: 

Summary

Jan Fahrenkrug:

The brain’s biological clock

Ugeskr Læger 2018;180:V03180212

Daily biological rhythms are controlled by a clock system, composed of a hierarchical multi-oscillator structure. Each cell in this system harbours a self-sustained autonomous molecular oscillator. Light adjusts the phase of the brain oscillator to the environmental light/dark cycle by intrinsically photosensitive retinal ganglion cells through their own photoreceptor, melanopsin, and by using the neuropeptide called pituitary adenylate cyclase-activating polypeptide as well as glutamate as neurotransmitters. The circadian synchronisation system is critical to health, and breakdown of the 24-hours temporal order could lead to pathological conditions.

Du skal være logget ind for at læse denne artikel
Log ind

Right side

af Thomas Olsen | 19/11
7 kommentarer
af Svend Erik Gundestrup | 19/11
12 kommentarer
af Anders Mark Christensen | 19/11
1 Kommentar
af Jens Meyer Svendsen | 17/11
1 Kommentar
af Peter Søndergaard | 17/11
1 Kommentar
af Tom Nygaard Kristensen | 16/11
1 Kommentar
af Susanne Udengaard Gydesen | 16/11
6 kommentarer
af Lars Otto Hutters | 16/11
2 kommentarer