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Akromegali

Forfatter(e)
Mai Christiansen Arlien-Søborg1, Anne Mohr Drewes1, Mogens Pfeiffer-Jensen2 & Jens Otto Lunde Jørgensen1 1) Klinik for Diabetes og Hormonsygdomme, Aarhus
Universitetshospital2) Reumatologisk Afdeling, Aarhus Universitetshospital

Ugeskr Læger 2018;180:V09170637
Reference: 
Ugeskr Læger 2018;180:V09170637
Sidetal: 

Mai Christiansen Arlien-Søborg, Anne Mohr Drewes,
Mogens Pfeiffer-Jensen & Jens Otto Lunde Jørgensen:

Acromegaly

Ugeskr Læger 2018;180:V09170637

Acromegaly is a rare and disabling disease with a plethora of symptoms and signs attributed to sustained elevations and actions of growth hormone and insulin-like growth factor 1. Acromegaly is characterised by excessive somatic growth and multiple comorbidities in addition to occasional compression of the optic nerve and hypopituitarism due to the underlying adenoma. The course of the disease is insidious, and a diagnostic delay of 5-10 years is typical, and this pre-diagnostic period is also associated with increased morbidity. Effective treatment is available, once the diagnosis is established.

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