Content area

|
|

CDKN2A-mutation hos en familie med arveligt malignt melanom

Forfatter(e)
Malene Djursby1, Karin Wadt1, Henrik Lorentzen2, Åke Borg3, Anne-Marie Gerdes1 & Lotte Krogh4 1) Klinisk Genetisk Afdeling, Rigshospitalet 2) Dermato-venerologisk Afdeling S, Aarhus Universitetshospital 3) Onkologisk Afdeling, Lunds Universitet 4) Klinisk Genetisk Afdeling, Odense Universitetshospital Ugeskr Læger 2014;176:V10130587
Reference: 
Ugeskr Læger 2014;176:V10130587
Blad nummer: 
Sidetal: 
2-3
CDKN2A-mutation in a family with hereditary malignant melanoma
Malignant melanoma (MM) is a frequent form of cancer with increasing incidence. 6-10% of patients with MM report a family history of MM, and in most populations 2% of unselected cases of MM carry a CDKN2A mutation. We present a family with 24 cases of MM in nine persons from several generations, caused by a previously undescribed germ-line intronic mutation in CDKN2A. Through genetic counselling and genetic testing
Du skal være logget ind for at læse denne artikel
Log ind

Right side

af Hans Erik Brygger | 24/06
3 kommentarer
af Jennifer Vikre-Jørgensen | 22/06
2 kommentarer
af Susanne L. M. Bülow | 19/06
2 kommentarer
af Niels Ejnar Bie | 18/06
2 kommentarer
af Hanne Hermann | 17/06
1 Kommentar
af Julius Vindbjerg Nissen | 17/06
1 Kommentar
af Peter Tagmose Thomsen | 15/06
1 Kommentar