Rasmus Krøijer & Gunnar Baatrup:
The effect of primary colonoscopy versus follow-up colonoscopy in screening for colorectal cancer
Ugeskr Læger 2019;181:V07180521
Balancing indications for primary and follow-up colonoscopy in screening is important. In the lowest faecal test positive range of 100-150 ng/ml the rate of cancer is 1.9%, and the rate of intermediate and high-risk adenomas is 16.7%. International studies suggest, that only selected groups have comparable rates of significant findings at follow-up, and the risk normalises after one colonoscopy. In this review it is found, that in the current Danish screening programme for colon cancer the indications of primary screening and follow-up colonoscopy seem to be off-balance, but no national data exist on follow-up.