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Videnskab / 1. feb 2016

Effektiv smertelindring af capsaicinplaster mod postherpetisk neuralgi

Kasuistik
Dato
1. feb 2016
Forfattere
Hjalte Holm Andersen1, Carsten Sand2 & Jesper Elberling3 1) Center for Sanse-Motorisk Interaktion (SMI), Institut for Sundhedsvidenskab og Teknologi, Aalborg Universitet 2) Dermato-venerologisk Afdeling, Bispebjerg Hospital 3) Klinik for Allergi, Gentofte Hospital Ugeskr Læger 2016;178:V10150846
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Reference: 
Ugeskr Læger 2016;178:V10150846
Blad nummer: 
Sidetal: 
2-3
Effective pain relief of post-herpetic neuralgia with capsaicin patch
Topical 8% capsaicin is a recently approved treatment for post-herpetic neuralgia (PHN). Capsaicin works by causing extensive depolarization of nociceptive epidermal transient receptor potential cation channel V1-positive C-fibers leading to defunctionalization. In this case story a 51-year-old male patient, who was suffering from severe PHN pain and associated allodynia, experienced drastic pain relief upon treatment with topical 8% capsaicin. Pain associated with the patch application could be successfully alleviated by pretreatment with topical lidocaine/prilocaine 2.5% and/or oral tramadol. Topical 8% capsaicin should be considered as a feasible treatment option for PHN.

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