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Hyperfibrinolytisk dissemineret intravaskulær koagulation ved drukneulykker

Andreas Lund Hattesen1, Henrik Karsten Berg2, Lars Folkersen3 & Anne-Mette Hvas1 1) Blodprøver og Biokemi, Aarhus Universitetshospital 2) Anæstesiologisk Intensiv Afdeling, Odense Universitetshospital 3) Operation og Intensiv Øst, Aarhus Universitetshospital Ugeskr Læger 2017;179:V11160848
Ugeskr Læger 2017;179:V11160848
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Drowning-induced hyperfibrinolytic disseminated intravascular coagulation
Drowning induces respiratory failure with ensuing cardiac arrest, hypoxaemia and ischaemia. A coagulopathy is induced by ischaemia, acidosis and hypothermia, and clinically the patient develops uncontrolled bleeding due to hyperfibrinolysis. A rapid diagnostic approach is required to recognize this hyperfibrinolytic state, since initiation of treatment with antifibrinolytics and fibrinogen concentrate may bring this life-threatening condition to cessation.
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