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Metoclopramidinduceret respiratorisk dyskinesi

Mette Medom Vorre1 & Peter Lange2, 3 1) Klinisk Farmakologisk Afdeling,
Bispebjerg Hospital2) Medicinsk Afdeling, Herlev Hospital3) Afdeling for Epidemiologi, Institut
for Folkesundhedsvidenskab,
Københavns Universitet

Ugeskr Læger 2019;181:V09180626
Ugeskr Læger 2019;181:V09180626

Mette Medom Vorre & Peter Lange:

Metoclopramide-induced respiratory dyskinesia

Ugeskr Læger 2019;181:V09180626

This case report describes a patient, who presented with extrapyramidal side effects to the treatment with metoclopramide, which is used as an antiemetic, for gastroparesis and reflux. However, beyond its desired effect, serious neurological adverse reactions can be seen, which is why the European Medicines Agency and the Danish Medicines Agency have changed the recommendations for its use. If the extrapyramidal side effects include the respiratory muscles the patient‘s ability to breathe can be affected. If a patient receiving metoclopramide or antipsychotic drugs shows signs of tachypnoea or acute respiratory distress, the possibility of respiratory dyskinesia should always be considered.

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