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Smertemekanismer ved kroniske muskuloskeletale tilstande

Forfatter(e)
Professor Thomas Graven-Nielsen, professor Lars Arendt-Nielsen, professor Pascal Madeleine & professor Peter Svensson Aalborg Universitet, Institut for Sundhedsvidenskab og Teknologi, Center for Sanse-Motorisk Interaktion, og Aarhus Universitet, Odontologisk Institut, Afdeling for Klinisk Oral Fysiologi
Reference: 
Ugeskr Læger 2010;172(24):1824-1827
Blad nummer: 
Sidetal: 
1824-1827
Summary Pain mechanisms in chronic musculoskeletal conditions Ugeskr Læger 2010;172(24):1824-1827 Manifestations, quantitative assessment, genetic predisposition and mechanisms in musculoskeletal pain are presented. Quantitative sensory testing provides an opportunity to evaluate pain manifestations and mechanisms. Peripheral sensitization is important for the increased sensitivity of deep-tissue nociceptors and may, in part, explain hyperalgesia in localised pain conditions. Central sensitization mechanisms (spinal and supraspinal) are also important for the development of hyperalgesia and the pain that is present in more widespread pain conditions. Recent studies have highlighted the contributions of genetic factors to pain sensitivity. 7
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