Christian Stenør & Morten Togo Sørensen:
Sneddon’s syndrome in a young woman with antiphospholipid syndrome, ischaemic apoplexy and epileptic seizures
Ugeskr Læger 2019;181:V01190049
In this case report, a 28-year-old woman known with slight aortic regurgitation presented with partial complex epileptic seizures. On examination, livedo reticularis was noted, and cerebral MRI scans showed signs of clinical silent old lacunar infarctions. She was persistently triple positive for antiphospholipid antibodies in high titres and fulfilled the antiphospholipid syndrome criteria. The patient was diagnosed with Sneddon’s syndrome, which is a rare thrombotic vasculopathy characterised by the combination of cerebrovascular disease with livedo reticularis. Her seizures stopped, after anticoagulation therapy with warfarin was initiated.