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Behandling med statiner medfører en øget risiko for udvikling af type 2-diabetes

Forfatter(e)
Anette Bratt Solis1, Sascha Pilemann-Lyberg2 & Peter Gæde1 1) Medicinsk Afdeling, Slagelse Sygehus 2) Medicinsk Afdeling, Bispebjerg Hospital Ugeskr Læger 2014;176:V02130116
Reference: 
Ugeskr Læger 2014;176:V02130116
Blad nummer: 
Sidetal: 
227-231
Statin treatment causes an increased risk of type 2 diabetes
Statins are important in the prevention of cardiovascular (CV) disease. However, they are associated with new-onset diabetes in a dose-dependent manner, particularly when the patient is already in risk of contracting diabetes. Meta-analyses estimate that the risk is increased by 9%. In absolute terms one major CV event can be prevented per 155 patients treated with statins per year compared to one new case of diabetes per 498 patients treated per year. However, this new evidence should not affect the guidelines, where the goal of LDL-cholesterol concentration is < 1,8 mmol/l in patients with high CV risk.
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