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Anæstesi og porfyri

Hvilke lægemidler er sikre at anvende hos en patient med akut porfyri?
Signe Schjelde & Claus Lund 1) Anæstesiologisk Afdeling, Glostrup Hospital 2) Anæstesi og Intensiv Afdeling, Hvidovre Hospital Ugeskr Læger 2014;176:V11130677
Ugeskr Læger 2014;176:V11130677
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Anaesthetics and porphyria
Patients with acute porphyria are at risk of life-threatening attacks when exposed to stress, fast, infection, alcohol and especially some drugs, including older anaesthetics. Acute porphyrias are rare inherited diseases caused by inefficient enzymatic activity within the haem synthesis. During attacks the patient suffers from severe abdominal pain, cardiovascular instability, neurological symptoms etc. Preventive measures and treatment should be known to anaesthesiologists and surgeons in particular and known to other clinicians in general. In order to assist the clinicians, drug databases are available online.
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