Hastige samfundsændringer i Grønland i kombination med høj genetisk risiko har medført betydelig stigning i diabetesforekomsten i Inuitbefolkningen.
Forfatter(e)
Marit Eika Jørgensen1, 2 1) Steno Diabetes Center
2) Center for Sundhedsforskning i Grønland, Statens Institut for Folkesundhed
Ugeskr Læger 2014;176:V05140305
Diabetes in Greenland – from Alfred Bertelsen to molecular diagnostics
Health changes in Greenland have evolved in association with rapid social changes, ageing of the population, urbanisation, changes in diet and physical activity. Two population-based studies found a notably high prevalence of diabetes (9%) and pre-diabetes (19%) among Greenland Inuit. Contrary to most other studies, the highest prevalence of diabetes and pre-diabetes was observed in the least urbanised areas, and the traditional Inuit diet was associated with a higher risk of glucose intolerance. A recent study identified a strong association of a common TBC1D4 nonsense variant with diabetes.