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Perioperativ væsketerapi har indflydelse på koagulation, blodtab og komplikationer


Kirsten Cleemann Rasmussen, Tom Pedersen & Niels H. Secher

Anæstesi- og Operationsklinikken, Abdominalcentret, Rigshospitalet Ugeskr Læger 2018;180:V06170498

Ugeskr Læger 2018;180:V06170498
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Perioperative fluid therapy influences coagulation, blood loss and post-operative complications

Literature on fluid therapy for surgery is updated in regard to coagulation, blood loss and post-operative complications. Haemorrhage depends on the surgical intervention but also on the chosen fluid therapy with artificial colloids affecting coagulation competence and in turn the blood loss. Furthermore, a stable central blood volume as indicated by plasma pro-atrial natriuretic peptide requires a calculated fluid surplus by approximately 2.5 l. Randomized controlled trials recommend haemorrhage to be treated by administration of a crystalloid; however, if the calculated excess of fluid approaches 2 l, albumin may be added.

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