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Psykologiske, neurologiske og cellulære virkningsmekanismer ved mindfulnesstræning

Forfatter(e)
Rasmus Jentoft Boutrup1, Malene Munk Jørgensen1, Niels Gregersen2, Lars Frost3, 4, Heidi Aagaard5, Dorthe Djernis6, Anne Maj van der Velden 4, 7 & Jesper Dahlgaard1, 2
1) Center for Sundhedsfremme og Rehabilitering, VIA University College 2) Molekylær Medicinsk Forskningsenhed, Institut for Klinisk Medicin, Aarhus Universitetshospital 3) Hjerteklinikken, Medicinsk Afdeling, Regionshospitalet Silkeborg 4) Institut for Klinisk Medicin, Health, Aarhus Universitet 5) Rehabiliteringscenter for Muskelsvind, Aarhus 6) Institut for Geovidenskab og Naturforvaltning, Det Natur- og Biovidenskabelige Fakultet, Københavns Universitet 7) Psychiatric Institute, Oxford Universitet

Ugeskr Læger 2019;181:V11180784
Reference: 
Ugeskr Læger 2019;181:V11180784

Rasmus Jentoft Boutrup, Malene Munk Jørgensen,
Niels Gregersen, Lars Frost, Heidi Aagaard, Dorthe Djernis,
Anne Maj van der Velden & Jesper Dahlgaard:

Psychological, neurological and cell-mediated mechanisms by mindfulness-based therapy

Ugeskr Læger 2019;181:V11180784

In this review, we present clinical studies on mindfulness-based therapy (MBT) with a focus on mediating mechanisms for its health promoting effects. These constitute awareness, self-compassion, regulation of dysfunctional patterns of thoughts and emotions, neural network and cellular processes. Among cellular processes are inflammation, oxidative stress, mitochondrial dysfunction and telomere shortening, which all contribute to the molecular pathophysiology of several of today’s lifestyle diseases. Finally, we address applications, where strong evidence exists for the clinical impact of MBT.

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