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Susacs syndrom er en vigtig differentialdiagnose ved monosymptomatisk encefalopati hos yngre voksne

Caroline Ellinore Weinsjö1, Gitte Buhl-Jensen1, Marianne Wegener2, Christoffer Tanderup Nielsen3 & Daniel Kondziella4
1) Neurologisk Klinik, Rigshospitalet-Glostrup. 2) Øjenklinikken, Rigshospitalet-Glostrup. 3) Videncenter for Reumatologi og Rygsygdomme, Rigshospitalet. 4) Neurologisk Klinik, Rigshospitalet-Blegdamsvej

Ugeskr Læger 2019;181:V08180541

Ugeskr Læger 2019;181:V08180541
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Caroline Ellinore Weinsjö, Gitte Buhl-Jensen, Marianne Wegener, Christoffer Tanderup Nielsen & Daniel Kondziella:

Susac syndrome is an important differential diagnosis in monosymptomatic encephalopathy in young adults

Ugeskr Læger 2019;181:V08180541

This is a case report of a 29-year-old man, who presented with progressive confusion, memory problems and personality changes during 1.5 months. Later, he developed bilateral hearing impairment but had no visual symptoms.
A brain MRI showed numerous small hyperintensities in both hemispheres, a retinal fluorescence angiography revealed multiple hyperfluorescent arterial occlusions, and an audiogram showed bilateral hearing impairment. The patient was treated for Susac syndrome with high-dose corticosteroids initially, followed by intravenous immunoglobulin and cyclophosphamide.

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