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Diagnostiske mål og døgnrytmer

Forfatter(e)
Henriette P. Sennels1, Henrik L. Jørgensen2 & Jan Fahrenkrug1 1) Klinisk Biokemisk Afdeling,
Bispebjerg og Frederiksberg Hospital2) Klinisk Biokemisk Afdeling,
Hvidovre Hospital

Ugeskr Læger 2018;180:V04180274
Reference: 
Ugeskr Læger 2018;180:V04180274
Blad nummer: 

Henriette P. Sennels, Henrik L. Jørgensen & Jan Fahrenkrug:

Diagnostic measurements and diurnal rhythms

Ugeskr Læger 2018;180:V04180274

Like the behaviour and physiology of the organism, biochemical parameters are subjected to diurnal variations through the daily 24-h light and dark cycle. Since blood sampling is carried out at all hours of the day and night, repeated blood testing from a patient throughout the day can be biased by diurnal variations, especially in parameters with high-amplitude 24-h rhythms. Concentration changes in biochemical parameters have thus to be interpreted in view of the 24-h rhythm, as only few recommendations regarding the optimal time of venipunctures and time-specific reference intervals exist.

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