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Behandling af glioblastom og andre kræftformer med tumor treating fields

Forfatter(e)
Anders Rosendal Korshøj1, 2, Slavka Lukacova3, Nikola Mikic1, Søren Ole Stigaard Cortnum1, Yasmin Lassen-Ramshad3, Trine Lignell Guldberg3, Kåre Eg Severinsen4, Axel Thielscher5, 6, Frantz Rom Poulsen7, Jens Christian Hedemann Sørensen1, 2 & Gorm Burckhard von Oettingen1
1) Neurokirurgisk Afdeling, Aarhus Universitetshospital 2) Institut for Klinisk Medicin, Health, Aarhus Universitet 3) Kræftafdelingen, Aarhus Universitetshospital 4) Neurologisk Afdeling, Aarhus Universitetshospital 5) Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital 6) Institut for Elektroteknologi, Danmarks Tekniske Universitet 7) Neurokirurgisk Afdeling, Odense Universitetshospital

Ugeskr Læger 2019;181:V07180481
Reference: 
Ugeskr Læger 2019;181:V07180481

Anders Rosendal Korshøj, Slavka Lukacova, Nikola Mikic,
Søren Ole Stigaard Cortnum, Yasmin Lassen-Ramshad,
Trine Lignell Guldberg, Kåre Eg Severinsen, Axel Thielscher, Frantz Rom Poulsen, Jens Christian Hedemann Sørensen &
Gorm Burckhard von Oettingen:

Tumor treating fields in cancer treatment in Denmark

Ugeskr Læger 2019;181:V07180481

Tumor treating fields (TTFields) is a new non-invasive approach to cancer treatment. TTFields are low-intensity (1-5 V/m), intermediate frequency (150-200 kHz) alternating electric fields delivered locally to the tumor to selectively kill dividing cells and disrupt cancer growth. TTFields has proven safe and effective for newly diagnosed glioblastoma and is currently being tried for multiple other tumors. This review presents an introduction to TTFields, covering the main indications, the application method, the mechanism of action, the clinical results and the perspectives for implementation in Danish cancer treatment.

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