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Betydning af hyper- og hypoglykæmi for kognition og udvikling af demens hos patienter med type 2-diabetes

Forfatter(e)
Helena Zander Wodschow, Nicole Jacqueline Jensen, Malin Sofia Desirée Nilsson & Jørgen Rungby Endokrinologisk Afdeling,
Bispebjerg Hospital

Ugeskr Læger 2018;180:V08180566
Reference: 
Ugeskr Læger 2018;180:V08180566
Blad nummer: 

Helena Zander Wodschow, Nicole Jacqueline Jensen, Malin Sofia Desirée Nilsson & Jørgen Rungby:

The effect of hyper- and hypoglycaemia on cognition and development of dementia for patients with diabetes mellitus Type 2

Ugeskr Læger 2018;180:V08180566

Diabetes mellitus Type 2 is associated with cognitive decline and a risk for developing dementia. The reason for this correlation is poorly understood, but evidence suggests insulin resistance, hyperglycaemia and glucose variability as likely culprits, whereas hypoglycaemia is a marker for cognitive decline rather than the cause. Inflammation and microvascular damage are possible common pathologies.

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