Betydning af hyper- og hypoglykæmi for kognition og udvikling af demens hos patienter med type 2-diabetes
Helena Zander Wodschow, Nicole Jacqueline Jensen, Malin Sofia Desirée Nilsson & Jørgen Rungby:
The effect of hyper- and hypoglycaemia on cognition and development of dementia for patients with diabetes mellitus Type 2
Ugeskr Læger 2018;180:V08180566
Diabetes mellitus Type 2 is associated with cognitive decline and a risk for developing dementia. The reason for this correlation is poorly understood, but evidence suggests insulin resistance, hyperglycaemia and glucose variability as likely culprits, whereas hypoglycaemia is a marker for cognitive decline rather than the cause. Inflammation and microvascular damage are possible common pathologies.