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Diagnostik af von Willebrands sygdom

Forfatter(e)
Fie Juhl Vojdeman1, Malou Philips2, Eva Funding3 & Jens Peter Gøtze2 1) Klinisk Biokemisk Afdeling, Bispebjerg og Frederiksberg Hospital 2) Klinisk Biokemisk Afdeling, Rigshospitalet 3) Enhed for Trombose og Hæmostase, Rigshospitalet

Ugeskr Læger 2019;181:V12180877

Reference: 
Ugeskr Læger 2019;181:V12180877

Fie Juhl Vojdeman, Malou Philips, Eva Funding & Jens Peter Gøtze:

Diagnosing von Willebrand disease

Ugeskr Læger 2019;181:V12180877

Von Willebrand disease (VWD) is an inherited bleeding disorder with abnormal primary haemostasis due to defects in, or decreased concentration of the glycoprotein von Willebrand factor. In Denmark, the estimated prevalence of VWD is 1% corresponding to approximately 50,000 patients, but only a few hundred have been diagnosed, mostly due to prolonged bleeding after a trauma or during surgery. Thus, VWD is underdiagnosed in the general population. Improved anamnestic screening for bleeding disorders such as VWD in certain high-risk groups can facilitate institution of prophylactic treatment.

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