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Epidemisk stigning i forekomsten af carbapenemaseproducerende enterobakterier i Danmark

Mikala Wang1, Svend Ellermann-Eriksen1, Dennis Schrøder Hansen2, Anne Kjerulf3, David Fuglsang-Damgaard4, Anette Holm5, Claus Østergaard6, Bent Røder7, Ute Wolff Sönksen3, Mette Detlefsen5, Frank Hansen3, Henrik Hasman3, Anette Hammerum3 & Robert L. Skov3 1) Klinisk Mikrobiologisk Afdeling, Aarhus Universitetshospital 2) Klinisk Mikrobiologisk Afdeling, Herlev Hospital 3) Afdelingen for Antibiotikaresistens, Statens Serum Institut 4) Klinisk Mikrobiologisk Afdeling, Aalborg Universitetshospital 5) Klinisk Mikrobiologisk Afdeling, Odense Universitetshospital 6) Klinisk Mikrobiologisk Afdeling, Sygehus Lillebælt, Vejle 7) Klinisk Mikrobiologisk Afdeling, Slagelse Sygehus Ugeskr Læger 2016;178:V06160422
Ugeskr Læger 2016;178:V06160422
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Epidemic increase in the incidence of carbapenemase-producing Enterobacteriaceae in Denmark
Carbapenemase-producing Enterobacteriaceae (CPE) are extremely multiresistant bacteria with few or no treatment options. Infections with CPE are associated with a mortality of 40-50%. In Denmark, CPE were first detected in 2008. Prior to 2013 the CPE incidence was low, but since then the incidence has increased significantly. Seven outbreaks have occurred, and at least 25 patients have been infected or colonized. The rise in CPE incidence emphasizes the need for a national intervention to reduce the spread. This can be obtained through systematic surveillance, infection control and reduction of antibiotic consumption.
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