Ugeskr Læger 2014;176:V04140219
Marjolin’s ulcer in scarred tissue and non-healing ulcers
The term “Marjolin’s ulcer” describes the formation of a malignant tumour in chronically inflamed skin such as non-healing ulcers or previously traumatized, burned or scarred tissue. Usually the patient sustains tissue damage with scarring or chronic ulcer for several decades prior to diagnosis. Marjolin’s ulcers are generally recognized as very aggressive tumours with high mortality. A chronic ulcer or scar suddenly changing in characteristics should lead physicians to perform a diagnostic survey.