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Nonalkoholisk fedtleversygdom hos børn og unge

Jessica Björklund1, Tea Lund Laursen1, Konstantin Kazankov1, Karen Louise Thomsen1, Stephen Hamilton-Dutoit2, Elisabeth Stenbøg3* & Henning Grønbæk1* 1) Medicinsk Hepato-gastroenterologisk Afdeling, Aarhus Universitetshospital 2) Patologisk Institut, Aarhus Universitetshospital 3)Pædiatrisk Afdeling, Aalborg Universitetshospital Ugeskr Læger 2017;179:V11160796
Ugeskr Læger 2017;179:V11160796
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Non-alcoholic fatty liver disease in children and adolescents
Non-alcoholic fatty liver disease (NAFLD) is characterized by liver fat accumulation and non-alcoholic steatohepatitis (NASH) with inflammation and fibrosis, which may lead to cirrhosis also in childhood. NAFLD/NASH in children are related to obesity and the metabolic syndrome, and incidence and prevalence are expected to increase. Children having liver steatosis and elevated liver enzymes are most often asymptomatic, and a liver biopsy is necessary for correct diagnosis and staging. The treatment should focus on lifestyle changes, as pharmacological therapy needs further evaluation.
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