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Screening for lungecancer med lavdosis-CT kræver grundige overvejelser

Forfatter(e)
Zaigham Saghir1, 2, Asger Dirksen1, Haseem Ashraf1, 3, Karen Skjøldstrup Bach4, John Brodersen5, Paul Frost Clementsen1, Martin Døssing6, Hanne Hansen7, Klaus Fuglsang Kofoed8, Klaus Richter Larsen9, Jann Mortensen10, Jakob Fraes Rasmussen5, Laura Hohwü Thomsen1, 11, Mathilde Marie Winkler Wille1, Niels Seersholm1, Birgit Guldhammer Skov12, Hanne Thorsen5, Philip Tønnesen13 & Jesper Holst Pedersen14 1) Lungemedicinsk Afdeling, Gentofte Hospital 2) Medicinsk Afdeling, Herlev Hospital 3) Bildediagnostisk Avdeling, Akershus Sykehus, Lørenskog, Norge 4) Radiologisk Afdeling, Gentofte Hospital 5) Institut for Folkesundhedsvidenskab, Afdeling for Almen Medicin, København Universitet 6) Medicinsk Afdeling, Nordsjælland Hospital, Frederikssund 7) Radiologisk Afdeling, Bispebjerg Hospital 8) Kardiologisk Afdeling, Rigshospitalet 9) Lungemedicinsk Afdeling, Bispebjerg Hospital 10) Klinisk Fysiologisk & Nuklearmedicinsk Afdeling, Rigshospitalet 11) Hjerte- og lungemedicinsk Afdeling, Hvidovre Hospital 12) Patologisk Afdeling, Bispebjerg Hospital 13) Dansk Center for Søvnmedicin, Glostrup Hospital 14) Thoraxkirurgisk Afdeling, Rigshospitalet Ugeskr Læger 2014;176:V06140341
Reference: 
Ugeskr Læger 2015;177:V06140341
Blad nummer: 
Sidetal: 
436-439
Lung cancer screening with low dose CT requires careful consideration
Results from the American National Lung Screening Trial (NLST) show a significant reduction in lung cancer and all-cause mortality in a high risk population screened with annual low-dose CT. Handling of pulmonary nodules, false positive tests, overdiagnosis, psychosocial consequences and cost-efficiency etc. are all aspects that require careful consideration. This paper gives an overview of the current knowledge on these issues. Before a recommendation can be made, we need an overall evaluation of both the benefits and harms in CT screening for lung cancer.
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