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Inflammatory bowel disease is associated with increased risk of acute pancreatitis

Inflammatory bowel disease (IBD) comprises ulcerative colitis and Crohn’s disease and is characterised by chronic intestinal inflammation with alternating periods of remission and relapse. IBD has been associated with a number of intestinal and extra-intestinal manifestations.

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The present meta-analysis investigates the risk of pancreatitis in patients with IBD. The authors identified four studies focusing on acute pancreatitis and none focusing on chronic pancreatitis. Based on a meta-analysis including data from app. 100,000 patients and controls they report that patients with Crohn’s disease are at a three-fold increased risk of developing acute pancreatitis, whereas patients with ulcerative colitis have a two-fold increased risk.

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Risk of pancreatitis in patients with inflammatory bowel disease
Josefine E. Pedersen, Lars H. Ängquist, Camilla B. Jensen et al

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