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Længere varighed af ubehandlet depression tyder på en dårligere prognose

Ifølge klinisk erfaring er varigheden af ubehandlet depression en vigtig prognostisk faktor med hensyn til respons på antidepressiv behandling, men der eksisterer overraskende lidt forskning på området.
Forfatter(e)
Simon Hjerrild & Poul Videbech Center for Psykiatrisk Forskning, Aarhus Universitetshospital, Risskov Ugeskr Læger 2014;176: V11120667
Reference: 
Ugeskr Læger 2014;176:V11120667
Blad nummer: 
Sidetal: 
434-436
The duration of untreated depression is associated with a poor treatment response
According to clinical lore the duration of untreated depression is associated with a poor treatment response. This is in accordance with the kindling hypothesis of depression. It is an important subject, since the duration of untreated depression as a potentially modifiable risk factor. Despite this, relatively few studies addressing the problem exist. While an association between the duration of untreated depression and treatment response generally is found, the uncontrolled and often retrospective nature of these studies makes it difficult to ascertain causality.
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