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Akral iskæmi med multiple mikrotromber og truende gangræn ved COVID-19-infektion

Forfatter(e)

Mathilde Borring Andersen1, Marie Louise Lund1, Søren Jacobsen2, Thomas Kümler3, Stine Simonsen4 & Pernille Ravn1

1) Medicinsk Afdeling, Infektionsmedicinsk Afsnit, Herlev-Gentofte Hospital, 2) Reumatologisk Klinik, Rigshospitalet, 3) Hjertemedicinsk Afdeling, Herlev-Gentofte Hospital, 4) Afdeling for Allergi, Hud- og Kønssygdomme, Herlev-Gentofte Hospital

Ugeskr Læger 2020;182:V05200379

Reference: 
Ugeskr Læger 2020;182:V05200379
Acral ischaemia with multiple microthromboses and imminent gangrene in a 73-year-old woman with COVID-19

Mathilde Borring Andersen, Marie Louise Lund, Søren Jacobsen, Thomas Kümle, Stine Simonsen & Pernille Ravn

Ugeskr Læger 2020;182:V05200379

This is a report of an atypical presentation of COVID-19. The patient had sparse pulmonary symptoms despite characteristic COVID-19 lesions on CT-thorax and developed severe acral ischaemic change, after a few days of hospitalisation. The condition could not be explained by classical sepsis with hypotension and hypoperfusion, disseminated intravascular coagulation, vasculitis, endocarditis or severe peripheral arteriosclerosis. A skin biopsy showed microthrombosis, interpreted as an activation of the coagulation system associated with COVID-19. Apparently, there are multiple COVID-19 phenotypes.

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