Ugeskr Læger 2016;178:V09150730
Antiphospholipid syndrome and pregnancy
Antiphospholipid syndrome (APS) is the association of antiphospholipid antibodies with thromboses and/or obstetric morbidity. Obstetric morbidity includes recurrent first trimester loss, stillbirth, intrauterine death, pre-eclampsia, premature birth and fetal growth restriction. Although current treatment regimens including aspirin and low-molecular weight heparin have improved pregnancy outcomes, 30% of affected women have pregnancy complications. Women with APS are therefore high-risk pregnancies who should be monitored in specialist centres according to international standards.