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Aquagenic wrinkling of the palms er en sjælden hudlidelse associeret til cystisk fibrose

Forfatter(e)

Anne Sofie Frølunde1, Lise Graversen2, Kristine Appel Uldall Pallesen1 & Mette Sommerlund1

1) Hud- og Kønssygdomme, Aarhus Universitetshospital, 2) Klinisk Genetisk Afdeling, Aarhus Universitetshospital

Ugeskr Læger 2021;183:V12200978

Reference: 
UgeskrLæger 2021;183:V12200978
Blad nummer: 
Aquagenic wrinkling of the palms is a rare dermatological disease associated with cystic fibrosis

Anne Sofie Frølunde, Lise Graversen, Kristine Appel Uldall Pallesen & Mette Sommerlund

Ugeskr Læger 2021;183:V12200978

Aquagenic wrinkling of the palms was first described in 1974. This review summarises the present knowledge. Aquagenic wrinkling of the palms is most often associated with cystic fibrosis, but several other associated conditions are described. Patients report of pruritus, pain and discomfort in the palms after contact with water, and excessive wrinkling is visible. The prognosis is good, and symptoms often decrease in adulthood. A positive water exposure test will support the diagnosis, and the patient should be referred for dermatological investigation and genetic test for cystic fibrosis should be offered.

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