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Asfyksi og hypoksisk-iskæmisk encefalopati

Forfatter(e)

Ted Carl Kejlberg Andelius1, Kasper Jacobsen Kyng1, Christian Heiring2 & Tine Brink Henriksen1

1) Nyfødt Intensiv Afsnit, Børn og Unge, Aarhus Universitetshospital

2) Neonatalklinikken, Juliane Marie Centret, Rigshospitalet

Ugeskr Læger 2020;182:V12190704

Reference: 
Ugeskr Læger 2020;182:V12190704
Blad nummer: 
Asphyxia and hypoxic-ischaemic encephalopathy

Ted Carl Kejlberg Andelius, Kasper Jacobsen Kyng, Christian Heiring &
Tine Brink Henriksen

Ugeskr Læger 2020;182:V12190704

Hypoxic-ischaemic encephalopathy is a common cause of death and disability in newborns. Brain damage related to a perinatal insult is the result of a dynamic process, and its progressing development over time allows for specific interventions to reduce total damage, as described in this review. Despite therapeutic hypothermia which currently is the only treatment available, a considerable number of newborns still have adverse outcomes. Prognosis is evaluated by clinical examination and paraclinical investigations. There is still a need for novel treatments and better prognostic and diagnostic tools to improve outcome.

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