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Brug af glykeret hæmoglobin-måling i praksis

Forfatter(e)

Silje H. Christensen1, Nete Hornung2, Jurgita Janukonyté3, Else Marie Vestergaard4 & Mie Samson1

1) Blodprøver og Biokemi, Aarhus Universitetshospital, 2) Klinisk Biokemisk Afdeling, Hospitalsenhed Vest, 3) Blodprøver og Biokemi, Hospitalsenhed Midt, 4) Blodprøver og Biokemi, Regionshospitalet Horsens

Ugeskr Læger 2021;183:V12200902

Reference: 
Ugeskr Læger 2021;183:V12200902
Blad nummer: 
Haemoglobin A1c measurements when to use and when not

Silje H. Christensen, Nete Hornung, Jurgita Janukonyté, Else Marie Vestergaard & Mie Samson

Ugeskr Læger 2021;183:V12200902

Haemoglobin A1c (HbA1c) reflects the glycaemic status of the latest 2-3 month and is used in both diagnosing and monitoring diabetes. Different circumstances may lead to spurious HbA1c results as summarised in this review. HbA1c is susceptible to changes in erythrocyte turnover (e.g. anaemia) regardless of measurement method, and to analytical interference (e.g. haemoglobin variants) depending on the method. The laboratory may detect and warn of suspected analytical interference. However, if the clinical presentation and glycaemic measures are incoherent, spurious HbA1c should be suspected and fasting glucose should be measured.

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