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Cancerimmunterapi til behandling af hæmatologisk cancer

Forfatter(e)
Morten Orebo Holmström*, 1, 2, Uffe Klausen*, 2, Nicolai Grønne Jørgensen2, Staffan Holmberg2, 3, Jacob Grauslund2, Özcan Met2, 4, Inge Marie Svane2, 4, Lars Møller Pedersen2, Lene Meldgaard Knudsen2, Hans Carl Hasselbalch1 & Mads Hald Andersen2, 5
1) Hæmatologisk Afdeling, Sjællands Universitetshospital, Roskilde
2) Nationalt Center for Cancer Immun Terapi, Hæmatologisk Afdeling, Herlev Hospital
3) DTU Nanotech, Division for Immunology and Vaccinology, DTU
4) Onkologisk Afdeling, Herlev Hospital
5) Institut for Immunologi og Mikrobiologi, Det Sundhedsvidenskabelige Fakultet, Københavns Universitet

Ugeskr Læger 2019;181:V06180421
Reference: 
Ugeskr Læger 2019;181:V06180421

Morten Orebo Holmström#, Uffe Klausen#,
Nicolai Grønne Jørgensen, Staffan Holmberg, Jacob Grauslund, Özcan Met, Inge Marie Svane, Lars Møller Pedersen,
Lene Meldgaard Knudsen, Hans Carl Hasselbalch &
Mads Hald Andersen:

Cancer immune therapy for the treatment of haematological malignancies

Ugeskr Læger 2019;181:V06180421

Cancer immune therapy is now used routinely for the treatment of several solid malignancies, albeit just recently having entered the clinic for treatment of haematological malignancies. Several studies demonstrate that cancer immune therapy is a promising treatment modality for the latter. Especially treatment with chimeric antigen receptor
T cells for acute lymphoblastic leukaemia and lymphoma is promising. Other promising treatment modalities are immune check point inhibitors for both lymphoid and myeloid malignancies, as well as therapeutic cancer vaccination targeting tumour antigens.

#) Contributed equally

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