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Copeptin er en ny diagnostisk biomarkør for diabetes insipidus

Forfatter(e)

Jelena Stankovic1, Søren Rittig2, Jens Otto Lunde Jørgensen1 & Esben Søndergaard1, 3

1) Diabetes og Hormonsygdomme, Aarhus Universitetshospital, 2) Børneafdelingen, Aarhus Universitetshospital, 3) Steno Diabetes Center, Aarhus

Ugeskr Læger 2020;182:V09200670

Reference: 
Ugeskr Læger 2020;182:V09200670
Blad nummer: 
Copeptin is a new diagnostic biomarker for diabetes insipidus

Jelena Stankovic, Søren Rittig, Jens Otto Lunde Jørgensen & Esben Søndergaard

Ugeskr Læger 2020;182:V09200670

Differential diagnosis of diabetes insipidus is challenging. The water deprivation test is the current gold standard, but the test is cumbersome, and the diagnostic performance is poor. Copeptin, which is a split product of the vasopressin pre-propeptide, appears to be a robust biomarker in the circulation and a promising tool for the diagnosis of patients with polyuria and polydipsia, especially when measured in conjunction with intravenous infusion of arginine, as summarised in this review.

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