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Coronary computed tomography angiography without significant stenosis predicts favourable three-year prognosis

Jeppe Maagaard Kristiansen1, Tomas Zaremba1, Martin Berg Johansen2, Hans-Henrik Tilsted1 & Svend Eggert Jensen1 FROM: 1) Department of Cardiology, Aalborg University Hospital, 2) Center for Cardiovascular Research, Aalborg University Hospital


The objective of this study was to evaluate the incidence of
death, cardiovascular events and the use of later non-scheduled imaging for coronary artery disease (CAD) in patients suspected for CAD and discharged without a need for further examination or treatment from an outpatient clinic following coronary computed tomography angiography (CCTA).

Material and methods

This was a retrospective cohort study among patients discharged from an outpatient clinic after CCTA at our institution during 2009 and 2010. Follow-up was performed using nationwide Danish registers.


A total of 683 (68.2%) out of 1001 patients were discharged from the outpatient clinic after CCTA with no need for further examination. These patients were included in our study. After a median follow-up of 37 months, a low all-cause mortality of 3.7 per 1,000 person-years was found. There was only one case of acute myocardial infarction and no cases of death related to cardiovascular disease. A total of 5.0% of the patients later underwent non-scheduled imaging, predominantly invasive coronary angiography. No patients had revascularisation performed during the study period.


Patients with suspected CAD discharged after CCTA with no need for further examination have a favourable cardiovascular prognosis.


Not relevant.

Trial registration

Not relevant.

Correspondence: Jeppe Maagaard Kristiansen. E-mail:

Conflicts of interest: none. Disclosure forms provided by the authors are available with the full text of this article at

Reference: Dan Med J 2014;61(8):A4884

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