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Demaskering af Whipples sygdom efter start på prednisolon

Forfatter(e)

Camilla Grauslund1, Nurcan Aydemir1, Signe Lehn2 & Terese Katzenstein3

1) Medicinsk Afdeling, Slagelse Sygehus, 2) Patologisk Afdeling, Roskilde Sygehus, 3) Infektionsmedicinsk Afdeling, Rigshospitalet

Ugeskr Læger 2020;182:V05200321

Reference: 
UgeskrLæger 2020;182:V05200321
Blad nummer: 
Unmasking of Whipples disease after start of prednisolone therapy

Camilla Grauslund, Nurcan Aydemir, Signe Lehn & Terese Katzenstein

Unmasking of Whipples disease after start of prednisolone therapy

Ugeskr Læger 2020;182:V05200321

Whipples disease (WD) is a rare infectious disease with an annual incidence of 1-6:10.000.000. It is mostly found in middle aged, Caucasian males. The causative bacterial agent Tropheryma whipplei (TW) is common, but only few infected with TW develop actual WD pointing to host factors as essential. We present a case story of classic WD seen in a 48-year-old man presumed to have sarcoidosis and therefore treated with prednisolone which caused WD to flare up and ultimately unmask the disease.

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