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Der er forandringer i hjernens ledningsbaner ved skizofreni

Forfatter(e)
Bjørn H. Ebdrup1, 2, Nana Skovgaard3, Jayachandra M. Raghava1, 4 & Birte Glenthøj1 1) Center for Neuropsykiatrisk Skizofreniforskning CNSR & CINS, Psykiatrisk Center Glostrup 2) Psykiatrisk Center Hvidovre 3) Psykiatrisk Center København 4) Diagnostisk Afdeling, Enhed for Funktionel Billeddiagnostik, Glostrup Hospital Ugeskr Læger 2014;176:V05140279
Reference: 
Ugeskr Læger 2014;176:V05140279
Blad nummer: 
Sidetal: 
2-6
White matter alterations in schizophrenia
Schizophrenia is a brain disorder characterized by fundamental changes in thinking and beliefs. Alterations in white matter integrity may underlie the characteristic psychotic symptoms. This review focuses on diffusion tensor imaging studies in schizophrenia patients. Overall, schizophrenia appears to be associated with white matter deficits particularly in the fronto-temporal connections. To dissect potential medication effects from myelination deficits related to symptoms, longitudinal studies in initially antipsychotic-naive first-episode patients with schizophrenia are needed.
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