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Design af artificiel foetor flatus ved hjælp af flygtige bakterielle produkter

Ulrik Stenz Justesen Forskningsgruppen for anaerobe bakterier, Forskningsenheden for Klinisk Mikrobiologi, Klinisk Institut, Det Sundhedsvidenskabelige Fakultet, Syddansk Universitet, Odense Ugeskr Læger 2016;178:V68707
Ugeskr Læger 2016;178:V68707
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Design of artificial foetor flatus based on bacterial volatile compounds
INTRODUCTION: Excessive flatulence can be a huge social problem. The purpose of this study was to design artificial flatus from bacterial volatile compounds to stimulate research into neutralizing measures. MATERIAL AND METHODS: Anaerobic bacteria, representing a broad spectrum, from a recognized international culture collection was included. The strains were incubated in an anaerobic jar. After 24 hours the lid was removed, and the odour was evaluated by a specialist in clinical microbiology. RESULTS: Four different anaerobic strains were chosen for further studies based on their individual odours. In total, seven different combinations of two or three strains were tested. The combination of Bacteroides fragilis ATCC 25285, Clostridium difficile ATCC 700057 and Fusobacterium necrophorum ATCC 25286 was chosen as it had a suitably foul odour. CONCLUSION: It is possible to design artificial flatus from bacterial volatile compounds. The method is easy and inexpensive and can stimulate further research into neutralizing measures.TRIAL REGISTRATION: none.FUNDING: none.
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