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Endometrioidt adenokarcinom med samtidigt nongestationelt koriokarcinom i uterus

Forfatter(e)
Gudrun Neumann1, Charlotte Brasch-Andersen2, Christina Fagerberg2 & Doris Schledermann3
1) Gynækologisk-Obstetrisk Afdeling, Odense Universitetshospital 2) Klinisk Genetisk Afdeling, Odense Universitetshospital 3) Afdeling for Klinisk Patologi, Odense Universitetshospital

Ugeskr Læger 2019;181:V03190167
Reference: 
Ugeskr Læger 2019;181:V03190167

Gudrun Neumann, Charlotte Brasch-Andersen, Christina Fagerberg & Doris Schledermann:

Endometrioid adenocarcinoma with a co-existing non-gestational choriocarcinoma in uterus

Ugeskr Læger 2019;181:V03190167

This is a case report of a 56-year-old woman with a history of postmenopausal bleeding, who presented with an endometrioid adenocarcinoma and a co-existing non-gestational choriocarcinoma. We performed robotic assisted hysterectomy, bilateral oophorectomy and pelvic lymphadectomy, and histopathologic examination revealed a malignant tumour showing an endometrioid adenocarcinoma grade 2 with a minor component of choriocarcinoma incorporated into the adenocarcinoma. We compared data from exome sequencing of DNA from tumour and blood to show, that the choriocarcinoma component was most likely non-gestational.

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