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Fibromyalgi som neurogen smertetilstand

Overlæge Kirstine Amris & læge Anders Jespersen Parker Instituttet og Frederiksberg Hospital, Reumatologisk Afdeling H
Ugeskr Læger 2010;172(24):1832-1835
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Summary Fibromyalgia as a neuropathic pain condition Ugeskr Læger 2010;172(24):1832-1835 Fibromyalgia is characterised by chronic widespread pain and mechanical hyperalgesia. It is associated with a higher pain intensity, fewer pain-free intervals and more pronounced pain-related interference in function than other musculoskeletal pain conditions. Increasing evidence supports an underlying augmented central pain processing which includes sensitization of pain-transmitting neurons and dysfunction of pain inhibitory pathways. If this permanent change in the function of the nociceptive system is shown to equal fibromyalgia, the condition may be considered a neuropathic pain condition.
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