Content area

|
|

Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis

Forfatter(e)
Claus Moser1, Tom Hartvig2, Jens Schierbeck3 & Niels Høiby1, 4 1) Klinisk Mikrobiologisk Afdeling, Rigshospitalet 2) Anæstesiologisk Afdeling, Intensiv 4131, Rigshospitalet 3) Anæstesiologisk-intensiv Afdeling V, Odense Universitetshospital 4) Institut for Immunologi og Mikrobiologi, Københavns Universitet Ugeskr Læger 2016;178:V05150426
Reference: 
Ugeskr Læger 2016;178:V05150426
Blad nummer: 
Sidetal: 
2-6
Augmented renal clearance of antibiotics may lead to inadequate dosings for patients with sepsis
Early, relevant antibiotic treatment is of pivotal significance for survival for patients with sepsis. Recent reports reveal, that critically ill patients may need substantially higher dosing of antibiotics than the usual standards. The back­ground is the newly described augmented renal clearance (ARC), which can be observed in critically ill patients with sepsis. ARC results in significantly reduced antibiotic concentrations in patients with sepsis and can potentially have fatal consequences. The purpose of this paper is to make medical doctors aware of the phenomenon and to compensate for the increased antibiotic clearance.
Du skal være logget ind for at læse denne artikel
Log ind

Right side

af Karen Flink Konstantin-Hansen | 09/04
5 kommentarer
af Tata Marion Ringberg | 08/04
3 kommentarer
af Per Prætorius Clausen | 07/04
6 kommentarer
af Karen Flink Konstantin-Hansen | 06/04
1 Kommentar
af Qazaz Mirza | 05/04
2 kommentarer
af Lise Kay | 05/04
2 kommentarer