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Intrakraniale meningeomer

Mikkel Schou Andersen1, Christian Bonde Pedersen1, Tiit Mathiesen2, Lars Poulsgaard2, Bjarne Winther Kristensen3, Bo Halle1 & Frantz Rom Poulsen1 1) Neurokirurgisk Afdeling, Odense Universitetshospital2) Neurokirurgisk Afdeling, Rigshospitalet3) Afdeling for Klinisk Patologi, Odense Universitetshospital

Ugeskr Læger 2019;181:V07180489
Ugeskr Læger 2019;181:V07180489
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Mikkel Schou Andersen, Christian Bonde Pedersen,
Tiit Mathiesen, Lars Poulsgaard, Bjarne Winther Kristensen,
Bo Halle & Frantz Rom Poulsen:

Intracranial meningiomas

Ugeskr Læger 2019;181:V07180489

Meningiomas are the most frequent intracranial non-glial tumours. They are derived from arachnoid cap cells and are classified according to WHO histology-based classification. The epigenetic technique DNA methylation profiling has shown improved prognostic value in comparison to the current WHO classification. Total surgical tumour removal is still golden standard in meningioma treatment with radiation as a supplement for WHO high-grade patients and inoperable patients. Efficient medical alternatives to surgery are not yet available, but future research may provide new strategies to be explored.

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