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Isogen forhudstransplantation mellem énæggede tvillinger diskordante for hypospadi

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Yazan F. Rawashdeh, Gitte Møller Hvistendahl & Lars Henning Olsen

Børneurologisk Sektion, Urinvejskirurgisk Afdeling, Aarhus Universitetshospital

Ugeskr Læger 2021;183:V10200788

Reference: 
Ugeskr Læger 2021;183:V10200788
Blad nummer: 
Foreskin transplantation between monozygotic twins discordant for hypospadias

Yazan F. Rawashdeh, Gitte Møller Hvistendal & Lars Henning Olsen

Ugeskr Læger 2021;183:V10200788

This is a case report of monozygotic twins discordant for hypospadias, where the afflicted twin, a 33-year-old male, needed extensive redo urethral reconstruction. A two-stage reconstruction was planned by using the twin brother's prepuce. The scarred urethra was replaced by the isograft, and one year later the second stage was completed. At five-year follow-up, there was good cosmesis, and the index patient reported excellent voiding and no fistulae or stenosis. Despite its rarity, foreskin transplantation between discordant monozygotic twins is possible and offers a unique and durable management opportunity.

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