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Kronisk obstruktiv lungesygdom og genetik

Forfatter(e)
Stud.med. Truls Ingebrigtsen, postdoc. Simon Francis Thomsen, professor Jørgen Vestbo & overlæge Vibeke Backer Bispebjerg Hospital, Lungemedicinsk Forskningsenhed, og Hvidovre Hospital, Hjerte-lunge-medicinsk Afdeling
Reference: 
Ugeskr Læger 2008;170(38):2971-2973
Blad nummer: 
Sidetal: 
2971-2973
Summary Genetics and chronic obstructive pulmonary disease Ugeskr Læger 2008;170(38):2971-2973 Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and is associated with an inflammatory response of the lungs primarily caused by cigarette smoking. Cigarette smoking is by far the most important environmental risk factor for COPD, but less than half of all heavy smokers develop COPD. This indicates a genetic contribution to the individual disease susceptibility. Although many genes have been examined, the puzzle of COPD genetics seems still largely unsolved. It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes.
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