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Kutan lupus erythematosus

Tatjana Sandreva1, Anne Voss2 & Anette Bygum1 1) Hudafdeling I og Allergicentret, Odense Universitetshospital 2) Reumatologisk Afdeling, Odense Universitetshospital Ugeskr Læger 2015;177:V12140680
Ugeskr Læger 2015;177:V12140680
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Cutaneous lupus erythematosus
Cutaneous lupus erythematosus (LE) is an autoimmune disease. The most common clinical forms are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE) and discoid LE (DLE). Cutaneous LE, mainly ACLE, can be the first sign of systemic LE (SLE). DLE and SCLE are less associated with development of SLE, however, up to 85% of patients with SLE have cutaneous manifestations. The aetiology is multifactorial. Drugs such as proton pump inhibitors can induce SCLE, while UV-light and smoking can worsen the lesions. Treatment includes preventive strategies in addition to topical steroids and systemic hydroxychloroquine.
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