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Lamivudinbehandling af en hepatitis Bs- antigen-positiv patient med reaktiv artritis

Forfatter(e)
1. reservelæge Christian Borup & overlæge Anders Siboni Sygehus Sønderjylland Haderslev, Medicinsk Afdeling
Reference: 
Ugeskr Læger 2008;170(48):3940-3941
Blad nummer: 
Sidetal: 
3940-3941
Summary Lamivudine treatment of a HBs antigen positive man with reactive arthritis Ugeskr Læger 2008;170(48):3940-3941 A 46-year-old man who was HBs antigen positive since childhood had painful talocrural arthritis that was considered re-active to HBs antigen. Lamivudine treatment was started and HBV-DNA disappeared from the blood, and the joint swellings disappeared. HBe antibody disappeared after eight months. After one year and nine months lamivudine was discontinued, resulting in a flare of the hepatitis after 56 days: HBV-DNA rose to 40 million copies per ml and HBe antigen became positive. Lamivudine was reinstituted, resulting in normalization of ALAT and lowering of HBV-DNA under detection level.
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