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Mastocytose

Forfatter(e)
Sigurd Broesby-Olsen1, 2, Thomas Kielsgaard Kristensen2, 3, Lone Agertoft2, 4, Michael Boe Møller2, 3, Anne Pernille Hermann2, 5, Trine Torfing2, 6, Troels Havelund2, 7, Charlotte G. Mørtz1, 2,, Carsten Bindslev-Jensen1, 2 & Hanne Vestergaard2, 8 1) Hudafdeling I og Allergicentret, Odense Universitetshospital 2) Mastocytosecentret, Odense Universitetshospital 3) Afdeling for Klinisk Patologi, Odense Universitetshospital 4) H.C. Andersen Børnehospital, Odense Universitetshospital 5) Endokrinologisk Afdeling, Odense Universitetshospital 6) Radiologisk Afdeling, Odense Universitetshospital 7) Afdeling for Medicinske Mavetarmsygdomme, Odense Universitetshospital 8) Hæmatologisk Afdeling, Odense Universitetshospital Ugeskr Læger 2016;178:V10150854
Reference: 
Ugeskr Læger 2016;178:V10150854
Blad nummer: 
Sidetal: 
2-6
Mastocytosis
Mastocytosis is a heterogeneous disease with an increased number and activation of mast cells. Subtypes range from benign to rare aggressive forms, and the disease may affect people of all ages. The pathogenesis involves mutations in the KIT gene in both children and adult patients. Estimated prevalence is one per 10,000, but the disease is very likely underdiagnosed. The diagnosis may be challenging and patients may present to several medical specialties. This article presents an overview of clinical signs and symptoms as well as a diagnostic algorithm and treatment options of mastocytosis.
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