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Mekanismer bag rygsygdomme med fokus på Modicforandringer

Tom Bendix1 & Claus Manniche2 1) Videncenter for Reumatologi og Rygsygdomme, Rigshospitalet, Glostrup, og Københavns Universitet 2) Rygcenter Syddanmark, Sygehus Lillebælt, Middelfart, og Syddansk Universitet Ugeskr Læger 2015;177:V03150261
Ugeskr Læger 2015;177:V03150261
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Mechanism of low-back pain with focus on Modic changes
Low-back pain (LBP) pathology and pain have previously been connected with physical strain. The coping was therefore characterized by »be careful!« messages. In the 90s it was shown that these physical loads virtually did not mean anything regarding disc degeneration, although loads may create LBP episodes. Genetic aspects and the demon­stration in 2006 that Modic changes (MC) generally corre­lated with LBP changed our perception, especially because antibiotics seemed to be effective in MC. Moreover, the role of cytokines is becoming increasingly clear. The following years will be very exciting.
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