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Metformin og obstetriske patienter

Metforminbehandling af gravide.
Forfatter(e)
Katrine Dahl Pedersen1, Nathalie Søderhamn Bülow2, Kasper Aaboe2, Julie Galsgaard3, Helle Sand Odgaard4, Elisabeth Reinhardt Mathiesen5 & Jeannet Lauenborg2 1) Afdeling for Kvindesygdomme og Fødsler, Aarhus Universitetshospital 2) Gynækologisk/obstetrisk Afdeling, Herlev Hospital 3) Praksis Frederiksberg 4) Gynækologisk Obstetrisk Afdeling, Aalborg Universitetshospital 5) Center for Gravide med Diabetes, Endokrinologisk Afdeling, Rigshospitalet Ugeskr Læger 2015;177:V05150438
Reference: 
Ugeskr Læger 2015;177:V05150438
Blad nummer: 
Sidetal: 
2-5
Metformin and the obstetric patient
Polycystic ovary syndrome (PCOS) is associated with insulin resistance, infertility, obesity and gestational complications. Metformin is widely used in fertility treatment of women with PCOS, due to a suggested powsitive effect of continued metformin treatment beyond the first trimester on pregnancy complications. Larger randomized trials have failed to confirm this. Metformin treatment has not been found to be superior to insulin treatment in women with gestational diabetes and may be associated with long-term consequences in the children in the form of overweight and disturbed glucose metabolism.
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