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Mistanke om toksoplasmose under graviditet

Forfatter(e)

Mathilde Ørbæk1, Anna Sophie L. Kjær1, Henrik V. Nielsen2, Morten Lebech3, Terese Katzenstein1 & Anne-Mette Lebech1

1) Infektionsmedicinsk Klinik, Rigshospitalet, 2) Bakteriologisk, Mykologisk & Parasitologisk Specialdiagnostik, Statens Serum Institut, 3) Gynækologisk og Obstetrisk Afdeling, Sjællands Universitetshospital Roskilde

Ugeskr Læger 2020;182:V05190328

Reference: 
Ugeskr Læger 2020;182:V05190328
Blad nummer: 
Suspected toxoplasmosis in pregnancy

Ugeskr Læger 2020;182:V05190328

Mathilde Ørbæk, Anna Sophie L. Kjær, Henrik V. Nielsen, Morten Lebech, Terese Katzenstein & Anne-Mette Lebech:

Primary infection with Toxoplasma gondii in pregnant women can lead to vertical transmission of the parasites resulting in congenital toxoplasmosis. The frequency of foetal infection increases with gestational age at maternal infection, but the risk of developing clinical sequelae decreases. Data on antiparasitic treatment suggest, that maternal treatment reduces the risk of serious neurological sequelae or death in congenitally infected offspring. Aspects of diagnosis and antimicrobial treatment of T. gondii infection during pregnancy are summarised in this review.

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