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Multicentrisk retikulohistiocytose er en sjælden form for paraneoplasi

Anna Maria Andersson1, Tanja Todberg1, Kristian Kofoed1, Trine Zeeberg Iversen2, Martin Andersen3, Sofie Vetli Hjorth4 & Daniel El Fassi5, 6 1) Hud- og Allergiafdelingen, Herlev og Gentofte Hospital 2) Onkologisk Afdeling, Herlev og Gentofte Hospital 3) Videncenter for Reumatologi og Rygsygdomme, Rigshospitalet 4) Patologiafdelingen, Herlev og Gentofte Hospital 5) Hæmatologisk Afdeling, Herlev og Gentofte Hospital 6) Institut for Inflammationsforskning, Reumatologisk Afdeling, Rigshospitalet Ugeskr Læger 2018;180:V08170611
Ugeskr Læger 2018;180:V08170611
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Multicentric reticulohistiocytosis is a rare form of paraneoplasia
A 59-year-old woman developed a rash and severe arthralgia, which primarily affected her fingers. She displayed digital arthritis and nodules on the hands, chest, face, and oral cavity. Blood samples were normal. Skin biopsies revealed histiocytic proliferation. The surface marker profile and clinical findings were consistent with multicentric reticulohistiocytosis, which may occur as a paraneoplastic phenomenon. On workup, she was diagnosed with an otherwise asymptomatic stage IVC fallopian tube cancer. She experienced little effect of prednisolone, but her condition improved on antineoplastic treatment.
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