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Myalgisk encefalomyelitis eller kronisk træthedssyndrom

Forfatter(e)
Louise Brinth1, Henrik Nielsen2, Kim Varming3, Susanne E. Boonen4, Ana Gonzalez Ebsen5, Paula Fernández-Guerra5, 6, 7, Anne Sophie Schou3,
Jesper Mehlsen7, Niels Gregersen6, Ivan Brandslund8, 9 & Rikke Katrine Jentoft Olsen6
1) Klinisk Fysiologisk og Nuklearmedicinsk Afdeling, Gentofte Hospital 2) Hospitalet Danmark 3) Klinisk Immunologi, Aalborg Universitetshospital 4) Klinisk Genetisk Enhed, Pædiatrisk Afdeling, Sjællands Universitetshospital, Roskilde 5) Molekylær Medicinsk Forskningsenhed, Blodprøver og Biokemi, Aarhus Universitetshospital 6) Institut for Klinisk Medicin, Health, Aarhus Universitet 7) Hjertemedicinsk Afdeling, Bispebjerg Frederiksberg Hospital 8) Klinisk Immunologisk og Biokemisk Afdeling, Sygehus Lillebælt 9) Institut for Regional Sundhedsforskning, Syddansk Universitet

Ugeskr Læger 2019;181:V08180570

Reference: 
Ugeskr Læger 2019;181:V08180570
Blad nummer: 

Louise Brinth, Henrik Nielsen, Kim Varming, Susanne E Boonen, AC Gonzalez Ebsen, Paula Fernández-Guerra, Anne Sophie Schou, Jesper Mehlsen, Niels Gregersen, Ivan Brandslund & Rikke Katrine Jentoft Olsen:

Myalgic encephalomyelitis or chronic fatigue syndrome

Ugeskr Læger 2019;181:V08180570

In this review, we discuss the myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), which is characterised by extreme mental and physical fatigue with associated symptoms of pain, disturbed sleep, cognitive and autonomic dysfunction, as well as post-exertional malaise. This condition is often preceded by an infection, severe physiological and/or psychological strain. Over the last decades, research has demonstrated mitochondrial, neuroendocrine, immunological, and metabolic perturbations in patients with ME/CFS, giving hope for the development of new biomarkers and new treatment modalities.

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